Storage Condition
Refer MSDS for complete information
Synonyms
5-Methyluridine-1 13C, 201996-60-3
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
5-Methyluridine-1 13C is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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5-Methyluridine-1 13C usage and description
5-Methyluridine-1 13C is a modified nucleoside that contains a carbon isotope on the 13th position of the carbon chain. It is a derivative of uridine, one of the four nucleosides that make up RNA (ribonucleic acid). 5-Methyluridine-1 13C plays a crucial role in the metabolism of RNA, where it is involved in the biosynthesis of modified nucleosides, which have been shown to play important roles in gene expression, regulation, and translation.
The modified nucleoside has several applications in the field of biological research. It can be used in the synthesis of RNA molecules for structural analysis, as well as in the study of RNA-protein interactions. Additionally, 5-Methyluridine-1 13C can be used in metabolic labeling experiments to track RNA synthesis and turnover in living cells.
Chemically, 5-Methyluridine-1 13C is a pyrimidine nucleoside, containing a nitrogenous base (uracil) attached to a ribose sugar via a ฮฒ-N1-glycosidic bond. The carbon-13 isotope is incorporated into the ribose sugar, specifically on the C1 position. This modification does not significantly affect the overall structure or function of the nucleoside, but allows for more precise analysis and detection through NMR (nuclear magnetic resonance) spectroscopy.
