Storage Condition
Refer MSDS for complete information
Synonyms
N-Nitroso-N-methyl-3-aminopropionic Acid-d3, Methyl Ester
Application Notes
Useful research chemical for a range of applications
Hazard Compound
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N-Nitroso-N-methyl-3-aminopropionic Acid-d3, Methyl Ester is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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N-Nitroso-N-methyl-3-aminopropionic Acid-d3, Methyl Ester usage and description
N-Nitroso-N-methyl-3-aminopropionic Acid-d3, Methyl Ester, also known as NMDA-d3, is a deuterium-labeled derivative of N-Nitroso-N-methyl-3-aminopropionic Acid (NMDA), which is a potent neurotoxin. NMDA-d3 is a highly purified compound that is used in research studies to identify and quantify the presence of NMDA in various biological samples.
NMDA is a non-protein amino acid that has been found in several plant species, including the seeds of Lathyrus sativus, commonly known as sweet pea. The consumption of Lathyrus sativus has been linked to a disease known as lathyrism, which causes irreversible paralysis of the lower limbs. The main cause of lathyrism is the accumulation of NMDA in the body over time.
NMDA-d3 is used in research studies to better understand the mechanisms behind lathyrism and to identify potential treatments for the disease. It is also used in studies investigating the role of NMDA in neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
Chemically, NMDA-d3 is a stable compound with a molecular weight of 182.24 g/mol and a melting point of 138-140°C. It is soluble in water, ethanol, and methanol. NMDA-d3 is typically supplied as a white powder and is stored at -20°C to maintain its stability.
In conclusion, N-Nitroso-N-methyl-3-aminopropionic Acid-d3, Methyl Ester is a highly purified compound that is used in research studies to identify and quantify the presence of NMDA in various biological samples. It plays an important role in understanding the mechanisms of lathyrism and neurodegenerative diseases, and may ultimately lead to the development of effective treatments for these conditions.