M.F.
CโยนยณCโHโClโNโOโ
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
5-chloro-N-(2-chloro-4-nitrophenyl-1,2,3,4,5,6-13C6)-2-hydroxybenzamide
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Niclosamide-13C6 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Niclosamide-13C6 usage and description
Niclosamide-13C6 is a stable isotope-labeled version of Niclosamide, an anthelmintic drug used to treat tapeworm infections. This compound is labeled with six carbon-13 atoms, which can be used for various research purposes such as pharmacokinetic studies, drug metabolism studies, and drug-drug interaction studies.
Niclosamide-13C6 works by inhibiting the mitochondrial oxidative phosphorylation process in the tapeworms, leading to their death. This drug is effective against tapeworms such as Taenia saginata, Taenia solium, and Hymenolepis nana. It is also being studied for its potential use in treating other parasitic infections such as malaria and schistosomiasis.
In terms of chemical information, Niclosamide-13C6 has a molecular formula of C13H2Cl2N2O4, with a molecular weight of 356.06 g/mol. It is a white to pale yellow crystalline powder that is sparingly soluble in water and ethanol. This compound has a melting point of 225-230ยฐC and should be stored at room temperature in a dry and dark place.
Overall, Niclosamide-13C6 is a useful tool for research purposes and has the potential to be developed into a more effective treatment for parasitic infections.