Therapeutic Uses
Anti-Hypertensives
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
(2S,3aS,7aS)-1-((S)-2-Aminopropanoyl)octahydro-1H-indole-2-carboxylic Acid; (2S,3aS,7aS)-1-[(2S)-2-Amino-1-oxopropyl]
octahydro-1H-Indole-2-carboxylic Acid; Perindopril Impurity J
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for accurate information
Perindopril-N-desethylpentanoate is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Perindopril-N-desethylpentanoate usage and description
Perindopril-N-desethylpentanoate is a chemical compound that belongs to the class of angiotensin-converting enzyme (ACE) inhibitors. It is commonly used in the treatment of hypertension, heart failure, and coronary artery disease. The medication works by blocking the activity of ACE, an enzyme that converts angiotensin I to angiotensin II, which causes vasoconstriction and increases blood pressure. By inhibiting ACE, perindopril-N-desethylpentanoate helps to relax blood vessels and reduce blood pressure.
Perindopril-N-desethylpentanoate is rapidly absorbed after oral administration, and its maximum concentration is achieved within 1-2 hours. The medication is metabolized in the liver, and its primary metabolite, perindoprilat, is a potent ACE inhibitor with a longer half-life than perindopril-N-desethylpentanoate. The elimination half-life of perindopril-N-desethylpentanoate is approximately 3-4 hours, and the medication is excreted primarily in the urine.
Perindopril-N-desethylpentanoate is available in various forms, including tablets and capsules, and is typically taken once daily. The dosage may be adjusted based on the individual's response to the medication and their medical condition. Common side effects of perindopril-N-desethylpentanoate include dizziness, headache, nausea, and cough. It is important to note that the medication may interact with other drugs, including diuretics and potassium supplements, and should be used with caution in individuals with kidney or liver disease. Overall, perindopril-N-desethylpentanoate is an effective medication for the treatment of hypertension and related conditions, and its chemical properties make it a valuable tool in the management of cardiovascular disease.
