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Therapeutic Product Detail
Home Therapeutic Sofosbuvir CS-T-84999

Sofosbuvir 3’,5’-Bis-(S)-phosphate

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Product Code: CS-T-84999 Therapeutic Research Use Only
Sofosbuvir 3’,5’-Bis-(S)-phosphate
Category
Therapeutic
API Family
Sofosbuvir
Product Code
CS-T-84999
Research Status
For Laboratory Use

Sofosbuvir 3’,5’-Bis-(S)-phosphate

Sofosbuvir Therapeutic
Stock Status: : Enquire Live

CAT No.
CS-T-84999
CAS No.
1337482-17-3
Molecular Formula
C₃₄H₄₅FN₄O₁₃P₂
Molecular Weight
798.69
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
1337482-17-3
Product Code
CS-T-84999
M.F.
C₃₄H₄₅FN₄O₁₃P₂
M.W.
798.69
Smiles
CC(C)OC([C@H](C)NP(O[C@@H]1[C@H](O[C@@H](N2C(NC(C=C2)=O)=O)[C@@]1(F)C)COP(OC3=CC=CC=C3)(N[C@@H](C)C(OC(C)C)=O)=O)(OC4=CC=CC=C4)=O)=O
Category
Therapeutic
API Family
Sofosbuvir
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
isopropyl ((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate
References
CAS
PubChem
Wikipedia
Synonyms
Sofosbuvir 3',5'-Bis-O-Phosphoramidate
Application Notes
Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-ß-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Purity by HPLC
99.77%
Hazard Compound
Refer MSDS for accurate information.
Overview
Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-ß-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

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