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2(R)-Methyl Sofosbuvir



2(R)-Methyl Sofosbuvir Cas No.1496552-28-3

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  • Synonyms:(2R)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(S),2?R]-2?-deoxy-2?-fluoro-2?-methyl-P-phenyl-5?-uridylyl]-D-alanine-1-Methylethyl Ester; Sofosbuvir epimer
  • Chemical Name:propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
  • Application Notes:This is an epimer and impurity of Sofosbuvir. It can be used in the synthetic preparation of Sofosbuvir analogs
  • Product Category:Sofosbuvir Impurities

    2(R)-Methyl Sofosbuvir is identified by CAS No. 1496552-28-3 and is chemically known as (2R)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(S),2?R]-2?-deoxy-2?-fluoro-2?-methyl-P-phenyl-5?-uridylyl]-D-alanine-1-Methylethyl Ester; Sofosbuvir epimer, IUPAC Name: propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate.

    2(R)-Methyl Sofosbuvir is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Sofosbuvir.


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