Sofosbuvir Impurity C

1496552-28-3

CS-T-92617

C₂₂H₂₉FN₃O₉P

529.5

O[C@@H]1[C@H](O[C@H]([C@@]1(F)C)N2C(NC(C=C2)=O)=O)CO[P@](OC3=CC=CC=C3)(N[C@@H](C(OC(C)C)=O)C)=O

Impurity

Sofosbuvir

Refer MSDS for complete information.

"Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate"

Jiang, Xiangrui, et al.: Suzhou Vigonvita Life SciencesCo., CN 106188193 A 20161207 (2016)

(2R)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(S),2?R]-2?-deoxy-2?-fluoro-2?-methyl-P-phenyl-5?-uridylyl]-D-alanine-1-Methylethyl Ester; Sofosbuvir epimer

This is an epimer and impurity of Sofosbuvir. It can be used in the synthetic preparation of Sofosbuvir analogs

Refer MSDS for complete information.