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7(R)-epi Carfilzomib (2R,4S)-diol



7(R)-epi Carfilzomib (2R,4S)-diol Cas No.868540-17-4

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  • Synonyms:(S)-N-((R)-1-(((2R,4S)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
  • Chemical Name:(2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide
  • Application Notes:Carfilzomib (2R,4S)-Diol is an impurity of Carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
  • Product Category:Carfilzomib Impurities

    7(R)-epi Carfilzomib (2R,4S)-diol is identified by CAS No. 868540-17-4 and is chemically known as (S)-N-((R)-1-(((2R,4S)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide, IUPAC Name: (2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide.

    7(R)-epi Carfilzomib (2R,4S)-diol is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Carfilzomib.


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    The purchaser, user or importer of record is responsible for determining the accuracy of items at the time of ordering as it may change without notice as per current product specification.
    This product is solely intended for research purposes and is not approved for human consumption.







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