Carfilzomib (2S,4S)-Diol Hydrochloride

NA

CS-T-93646

C₄₀H₆₀ClN₅O₈

774.39

CC(C)C[C@H](NC([C@@H](NC(CN1CCOCC1)=O)CCC2=CC=CC=C2)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC(C)C)C([C@@](C)(O)CO)=O)=O)=O.[H]Cl

Impurity

Carfilzomib

Refer MSDS for complete information.

Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);

(S)-N-((S)-1-(((2S,4S)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide hydrochloride

Carfilzomib (2S,4S)-Diol Hydrochloride, the salt form of Carfilzomib (2S,4S)-Diol (C183495), and a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.

Refer MSDS for complete information.