CAS No.
[14653-77-1 (unlabelled)]
Storage Condition
Refer MSDS for complete information
Synonyms
2-[(3-Aminopropyl)amino]ethanethiol-13C3 Hydrochloride; WR 1065-13C3
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Amifostine Thiol-13C3 Dihydrochloride is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Amifostine Thiol-13C3 Dihydrochloride usage and description
Amifostine Thiol-13C3 Dihydrochloride is a therapeutic drug used in cancer treatment. The drug has a chemical formula of C5H12Cl2N2O3PS2 and is administered as an injection. The usage of Amifostine Thiol-13C3 Dihydrochloride is to reduce the negative side effects of radiation and chemotherapy on the body during cancer treatment. It is a cytoprotective agent that helps to protect healthy cells from damage caused by cancer treatment, thereby reducing the risk of developing secondary cancers.
Chemically, Amifostine Thiol-13C3 Dihydrochloride is a phosphorylated aminothiol that is rapidly dephosphorylated to its active form, thiol metabolite, in vivo. The drug works by scavenging free radicals that are produced during radiation and chemotherapy. It also helps to prevent DNA damage and apoptosis in healthy cells.
In addition to its use in cancer treatment, Amifostine Thiol-13C3 Dihydrochloride is also used in the treatment of xerostomia, a condition characterized by dry mouth, which is a common side effect of radiation therapy for head and neck cancers.
Like all drugs, Amifostine Thiol-13C3 Dihydrochloride has some side effects. The most common side effects include nausea, vomiting, hypotension, and allergic reactions. Patients should always consult with their healthcare provider before using this drug.
