CAS No.
[14653-77-1 (Unlabelled)]
Storage Condition
Refer MSDS for complete information
Synonyms
2-[(3-Aminopropyl)amino]ethanethiol DiHydrochloride-d4; WR 1065-d4
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Amifostine Thiol Dihydrochloride-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Amifostine Thiol Dihydrochloride-d4 usage and description
Amifostine Thiol Dihydrochloride-d4 is a deuterated analogue of Amifostine Thiol Dihydrochloride, which is an organic compound used in the treatment of cancer. It is a prodrug that is dephosphorylated by alkaline phosphatase to its active form, which acts as a potent cytoprotective agent. This compound is a potent scavenger of reactive oxygen species, which are known to cause cellular damage, and it has been shown to protect normal tissues from the harmful effects of radiation and chemotherapy.
Amifostine Thiol Dihydrochloride-d4 is used in various research studies where the use of a deuterated analogue is required. It is a useful tool for pharmacokinetic studies, as it allows the tracking of the compound’s metabolism and distribution in vivo. The deuterated analogue also has a unique mass spectral signature, which can be used to distinguish it from the non-deuterated compound in biological samples.
Chemically, Amifostine Thiol Dihydrochloride-d4 is a white crystalline powder with a molecular weight of 248.24 g/mol and a chemical formula of C5H10D4Cl2NOS. It is soluble in water and methanol, and it has a melting point of 245-247°C. This compound is stable under normal conditions of use and storage, and it should be stored in a dry and cool place. It is important to handle this compound with care, as it is a toxic and irritant substance.
