Storage Condition
Store at refrigerator (2-8°C) for long term storage
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for accurate information
Useful research chemical for a range of applications
Refund Policy
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7,8-Didehydro-10-hydroxy-naloxone usage and description
7,8-Didehydro-10-hydroxy-naloxone (DDHN) is a synthetic compound that acts as an opioid antagonist. It is a derivative of naloxone, a medication commonly used to reverse the effects of opioid overdose. DDHN has been shown to have a higher binding affinity for the mu-opioid receptor than naloxone, making it a more potent antagonist.
DDHN has potential use in the treatment of opioid addiction and overdose. It has been shown to reduce the rewarding effects of opioids, which can help prevent relapse in individuals in recovery. Additionally, it has been found to be effective in reversing respiratory depression caused by opioid overdose, which is the leading cause of death in opioid overdose cases.
Chemically, DDHN is a derivative of naloxone and has a molecular weight of 327.4 g/mol. Its chemical formula is C19H19NO4 and it has a melting point of 210-212°C. It is a pale yellow powder that is soluble in ethanol, acetone, and dimethyl sulfoxide (DMSO).
In conclusion, DDHN is a promising compound for the treatment of opioid addiction and overdose. Its high binding affinity for the mu-opioid receptor and ability to reduce the rewarding effects of opioids make it a potent antagonist. Further research is needed to fully understand its potential therapeutic applications and any potential side effects.
