CAS No.
[Unlabelled: 1443421-69-9]
Storage Condition
Refer MSDS for complete information
Synonyms
N6-Cyclopropyl-d4-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir-d4 Related Compound D
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Abacavir-d4 5โ-4-Chloro-6-methylpyrimidine-2,5-diamine is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Abacavir-d4 5โ-4-Chloro-6-methylpyrimidine-2,5-diamine usage and description
Abacavir-d4 5โ-4-Chloro-6-methylpyrimidine-2,5-diamine is a deuterated analog of Abacavir, which is an antiretroviral drug used to treat HIV-1 infection. Abacavir-d4 5โ-4-Chloro-6-methylpyrimidine-2,5-diamine is used to study the metabolism and pharmacokinetics of Abacavir. It is also used in research and development of new drugs for the treatment of HIV-1 infection.
Abacavir-d4 5โ-4-Chloro-6-methylpyrimidine-2,5-diamine is a pyrimidine nucleoside analog that inhibits the reverse transcriptase enzyme of the HIV virus. It is a prodrug that is converted into its active form, carbovir triphosphate, inside the HIV-infected cells. Carbovir triphosphate competes with natural nucleotides for incorporation into the viral DNA, leading to chain termination and inhibition of viral replication.
The chemical formula of Abacavir-d4 5โ-4-Chloro-6-methylpyrimidine-2,5-diamine is C14H9D4ClN4, and its molecular weight is 266.73 g/mol. It is a white to off-white powder, and it is soluble in water, methanol, and ethanol.
In conclusion, Abacavir-d4 5โ-4-Chloro-6-methylpyrimidine-2,5-diamine is a useful tool for studying the pharmacokinetics and metabolism of Abacavir, and it has potential for the development of new drugs for the treatment of HIV-1 infection.