API Family
Bendroflumethiazide
Storage Condition
Refer MSDS for complete information
Synonyms
4-Nitroso-3-((phenyl-d5)methyl)-6-(trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-Dioxide
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
N-Nitroso rac Bendroflumethiazide-D5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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N-Nitroso rac Bendroflumethiazide-D5 usage and description
N-Nitroso rac Bendroflumethiazide-D5 is a chemical compound used in research and clinical settings for its potential applications in the treatment of hypertension and other cardiovascular diseases. It is a stable isotope-labeled form of the drug bendroflumethiazide, which is a thiazide diuretic commonly used to treat high blood pressure.
The addition of the N-Nitroso group to bendroflumethiazide-D5 increases its bioavailability and potency, allowing for enhanced therapeutic effects. However, it is important to note that N-Nitroso compounds have been shown to have potential carcinogenic properties, and thus further research is needed to fully understand the safety and efficacy of this compound.
Chemically, N-Nitroso rac Bendroflumethiazide-D5 is a nitrosourea derivative with a molecular formula of C17H14D5ClN3O4S2. Its mechanism of action involves inhibiting the reabsorption of sodium and chloride ions in the distal convoluted tubules of the kidneys, leading to increased urinary excretion and decreased blood volume and pressure.
Overall, N-Nitroso rac Bendroflumethiazide-D5 shows promise as a potential therapeutic agent for hypertension and other cardiovascular conditions. However, further research is needed to fully understand its safety and efficacy, particularly with regards to its potential carcinogenic properties.