Product Detail
Dolutegravir-d3 RR Isomer
Stable Isotopes
Stock Status: Enquire
Live
For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
--
Storage
Refer MSDS for complete information.
Hazard Information
Refer MSDS for complete information.
Dolutegravir-d3 RR Isomer Product Information
Dolutegravir-d3 RR Isomer is listed under Stable Isotopes. It is associated with and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-96364.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Dolutegravir-d3 RR Isomer
CAS No.
-
CAT No.
CS-T-96364
Molecular Formula
C20H16D3F2N3O5
Molecular Weight
422.4
Category
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Dolutegravir-d3 RR Isomer
Hazard Compound
Refer MSDS for complete information.
Description
Overview
"Isotope labelled Dolutegravir RR Isomer is an isomer of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector."
Synonyms
"(4R,?12aR)?-N-?[(2,?4-Difluorophenyl)?methyl]?-?3,?4,?6,?8,?12,?12a-?hexahydro-?7-?hydroxy-?4-?methyl-?6,?8-?dioxo-?2H-pPyrido[1',?2':4,?5]?pyrazino[2,?1-?b]?[1,?3]?oxazine-?9-?carboxamide-d3"
Application Notes
"Isotope labelled Dolutegravir RR Isomer is an isomer of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector."
References
"Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);"
