rac-N-Desmethyl Bedaquiline-d6

2271264-46-9

CS-T-97647

C₃₁H₂₃D₆BrN₂O₂

547.52

OC(CCNC([2H])([2H])[2H])(C1=C2C=CC=CC2=CC=C1)C(C3=CC4=CC(Br)=CC=C4N=C3OC([2H])([2H])[2H])C5=CC=CC=C5

Metabolite

Bedaquiline

Refer MSDS for complete information.

1-(6-bromo-2-(methoxy-d3)quinolin-3-yl)-4-((methyl-d3)amino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol

"de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009)"

1-(6-bromo-2-(methoxy-d3)quinolin-3-yl)-4-((methyl-d3)amino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol

"rac-N-Desmethyl Bedaquiline-d6 is the labeled analog of rac-N-Desmethyl Bedaquiline (D231310), which is used in the synthesis of Bedaquiline (B119550), a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis."

Refer MSDS for complete information.