Storage Condition
Refer MSDS for complete information.
IUPAC Name
N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel-d7
References
"Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984); Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984); Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995); Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002); Stone, G.W., et al.:"
Synonyms
"(aR,ßS)-a-Hydroxy-ß-[[(2E)-1-oxo-2-hexen-1-yl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cy"
Application Notes
"N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel-d7 is the isotope labelled analog of N-Debenzoyl-N-[(3E)-hex-3-enoyl] Paclitaxel (D204050); an impurity of Paclitaxel (P132500) which is an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy."
Hazard Compound
Refer MSDS for complete information.