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Home Stable Isotopes CS-T-98368

trans-Ned-19-d8

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Product Code: CS-T-98368 Stable Isotopes Research Use Only
trans-Ned-19-d8
Category
Stable Isotopes
API Family
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Product Code
CS-T-98368
Research Status
For Laboratory Use

trans-Ned-19-d8

Stable Isotopes
Stock Status: : Enquire Live

CAT No.
CS-T-98368
CAS No.
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Molecular Formula
C30H23D8FN4O3
Molecular Weight
522.64
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-98368
M.F.
C30H23D8FN4O3
M.W.
522.64
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
trans-Ned-19-d8
References
"Rosen, D. et al.: J. Biol. Chem., 284, 34930 (2009); Naylor, E. et al.: Nat. Chem. Biol., 5, 220 (2009); Thai, T.L. et al.: Am. J. Physiol. Renal Physiol., 297, F510 (2009);"
Synonyms
"(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-(piperazinyl-d8)]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;"
Application Notes
"Labelled trans-Ned-19, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells."
Hazard Compound
Refer MSDS for complete information.
Overview
"Labelled trans-Ned-19, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells."

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