1-Acetyl-3-indoxyl-d5 Acetate

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CS-T-98673

C₁₂H₆D₅NO₃

222.25

[2H]C1=C(OC(C)=O)C2=C([2H])C([2H])=C([2H])C([2H])=C2N1C(C)=O

Stable Isotopes

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Refer MSDS for complete information.

1-Acetyl-3-indoxyl-d5 Acetate

"Jennifer, C. et al.: Biochem., 49, 393 (2010); Zgoda-Pols, J.R. et al.: Toxicol. Appl. Pharmacol., 255, 48 (2011)"

"1-[3-(Acetyloxy)-1H-indol-1-yl]-ethanone-d5; 1-Acetyl-1H-indol-3-ol-d5 Acetate (Ester); 1-Acetyl-indol-3-ol-d5 Acetate (Ester); 1-Acetyl-indoxyl-d5 Acetate; 1-[3-(Acetyloxy)-1H-indol-1-yl]ethanone-d5; 1,3-Diacetylindoxyl-d5; 1-Acetylindol-3-yl-d5 Acetate;"

"1-Acetyl-3-indoxyl-d5 Acetate is an intermediate in the synthesis of 3-Indoxyl Sulfate-d4 Potassium Salt (I655102), which is a labelled uremic toxin that acts as a potent endogenous agonist for the human aryl hydrocarbon receptor (AHR). Studies suggest that it is a sensitive and early biomarker of nephrotoxicity."

Refer MSDS for complete information.