3-(Aminocarbonyl)-1-(5-O-phosphono-ß-D-ribofuranosyl)pyridinium-d4 Inner Salt;,b-Nicotinamide-d4 Mononucleotide (d4-major),"b-Nicotinamide-d4 Mononucleotide is the labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.", Stable Isotopes
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