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For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-98865
M.F.
C30H19D8N5O7
M.W.
577.61
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
(+)-trans-anti-BPDE-N2-dG-d8
References
"Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Strasser, A. et al.: Cancer Epidemiol. Biomark. Prev., 22, 382 (2013);"
"Isotope labelled (+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, this compound used to obtain a better understanding of the effects of carcinnogen-DNA adducts."
Hazard Compound
Refer MSDS for complete information.
Overview
"Isotope labelled (+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, this compound used to obtain a better understanding of the effects of carcinnogen-DNA adducts."