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For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-99013
M.F.
C26H28D9FN6O6S2
M.W.
621.79
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
LY 2228820-d9
References
"Zhao, R. et al.: Drug Metab. Disp., 37, 1251 (2009); Ishitsuka, K. et al.: Br. J. Haematol., 141, 598 (2008); Mader, M. et al.: Bioorg. Med. Chem. Lett., 18, 179 (2008);"
"Laballed LY2228820, a novel and potent p38MAPK inhibitor with potent antiinflammatory activity. LY2228820 significantly inhibited phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, in both multiple myeloma (MM) cell lines and LT-BMSCs. LY2228820 is a potential candidate to improve MM patient outcome both by enhancing the effect of Bortezomib (B675700) and by reducing osteoskeletal events."
Hazard Compound
Refer MSDS for complete information.
Overview
"Laballed LY2228820, a novel and potent p38MAPK inhibitor with potent antiinflammatory activity. LY2228820 significantly inhibited phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, in both multiple myeloma (MM) cell lines and LT-BMSCs. LY2228820 is a potential candidate to improve MM patient outcome both by enhancing the effect of Bortezomib (B675700) and by reducing osteoskeletal events."
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