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Sulindac Sulfide-d6 (Major)

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Product Code: CS-T-99093 Stable Isotopes Research Use Only
Sulindac Sulfide-d6 (Major)
Category
Stable Isotopes
API Family
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Product Code
CS-T-99093
Research Status
For Laboratory Use

Sulindac Sulfide-d6 (Major)

Stable Isotopes
Stock Status: : Enquire Live

CAT No.
CS-T-99093
CAS No.
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Molecular Formula
C20H11D6FO2S
Molecular Weight
346.45
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-99093
M.F.
C20H11D6FO2S
M.W.
346.45
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Sulindac Sulfide-d6 (Major)
References
"Hermann, C., et al.: Oncogene, 17, 1769 (1998); Lim, T.J., et al.: Biochem. Pharmacol., 58, 1097 (1999); Zhang, Z. and DuBois, R.N.: Gastroenterology, 118, 1012 (2000);"
Synonyms
(Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic Acid-d6;
Application Notes
"Labelled analogue of Sulindac Sulfide, an active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP."
Hazard Compound
Refer MSDS for complete information.
Overview
"Labelled analogue of Sulindac Sulfide, an active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP."

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