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PU-H71-d7 Hydrate

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Product Code: CS-T-99119 Stable Isotopes Research Use Only
PU-H71-d7 Hydrate
Category
Stable Isotopes
API Family
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Product Code
CS-T-99119
Research Status
For Laboratory Use

PU-H71-d7 Hydrate

Stable Isotopes
Stock Status: : Enquire Live

CAT No.
CS-T-99119
CAS No.
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Molecular Formula
C18H14D7IN6O3S
Molecular Weight
535.41
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-99119
M.F.
C18H14D7IN6O3S
M.W.
535.41
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
PU-H71-d7 Hydrate
References
"Gewirth, D.T., et al.: J. Med. Chem., 49, 381 (2006), Taldone, T., et al.: Bioorh. Med. Chem., 17, 2225 (2009),"
Synonyms
"6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl-d7)-9H-purine-9-propanamine Hydrate;"
Application Notes
Labelled PU-H71 (P840122). It is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson's disease.
Hazard Compound
Refer MSDS for complete information.
Overview
Labelled PU-H71 (P840122). It is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson's disease.

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