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For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
1795144-12-5
Product Code
CS-T-99199
M.F.
C21H12D5N3O2S
M.W.
380.47
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
iCRT-14-d5
References
"Gonsalves, F.C. et al.: Proc. Natl. Acad. Sci. USA, 108, 5954 (2011); Watanabe, K. et al.: Proc. Natl. Acad. Sci. USA, 108, 5929 (2011);"
A labelled potent inhibitor of ß-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Studies suggest that it may directly influence the interaction between ß-catenin and TCF4. It induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.
Hazard Compound
Refer MSDS for complete information.
Overview
A labelled potent inhibitor of ß-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Studies suggest that it may directly influence the interaction between ß-catenin and TCF4. It induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.
![D-[UL-13C4]erythrose](https://structures.clearsynth.com/CS-OC-00087.PNG)