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CAS No.
-
Product Code
CS-T-99841
M.F.
C24H17D7FN7O
M.W.
452.54
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Selonsertib Isopropyl-d7
References
"Nelson, C. H. et al.: Clin Pharmacol Ther. 98, 630 (2015); Lin, J. H., et al.: Nephron. 129, 29 (2015)"
"Selonsertib Isopropyl d7 is an isotope labelled compound of Selonsertib (S253800). Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Selonsertib interacts with the catalytic kinase domain of ASK1 and prevents its phosphorylation and activation. As a result, the expression of genes involved in fibrosis, cellular proliferation, and apoptosis are down regulated."
Hazard Compound
Refer MSDS for complete information.
Overview
"Selonsertib Isopropyl d7 is an isotope labelled compound of Selonsertib (S253800). Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Selonsertib interacts with the catalytic kinase domain of ASK1 and prevents its phosphorylation and activation. As a result, the expression of genes involved in fibrosis, cellular proliferation, and apoptosis are down regulated."
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