Nicotinic Acid Adenine Dinucleotide-d4

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CS-T-99947

C₂₁H₂₂D₄N₆O₁₅P₂

668.43

Stable Isotopes

Refer MSDS for complete information.

Nicotinic Acid Adenine Dinucleotide-d4

"Dudev, T. et al.: J. Am. Chem. Soc., 132, 16533 (2010); Kerbey, A. et al.: Biochem. J., 154, 327 (1976); Lahiri, S.D. et al.: ACS Chem. Biol., 7, 571 (2012)"

"Adenosine 5'-(trihydrogen diphosphate), P'?5'-ester with 3-carboxy-1-ß-D-ribofuranosylpyridinium, inner salt-d4; 3-Carboxy-1-ß-D-ribofuranosylpyridinium hydroxide, 5'-ester with adenosine 5'-pyrophosphate, inner salt-d4; Pyridinium, 3-carboxy-1-ß-D-ribofu"

"Nicotinic Acid Adenine Dinucleotide-d4 is the isotope labelled analog of Nicotinic Acid Adenine Dinucleotide (N429270); an analog of ß-Nicotinamide Adenine Dinucleotide (N407775, Hydrate) which is a coenzyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate groups. ß-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. ß-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins."

Refer MSDS for complete information.