Storage Condition
Refer MSDS for complete information
Synonyms
5-(4-fluorophenyl)-1-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-2-isopropyl-4-phenyl-N-(phenyl-d5)-1H-pyrrole-3-carboxamide
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Atorvastatin-d5 (N-(phenyl-d5) Lactone is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Atorvastatin-d5 (N-(phenyl-d5) Lactone usage and description
Atorvastatin-d5 (N-(phenyl-d5) Lactone) is a deuterated form of the cholesterol-lowering drug Atorvastatin. Atorvastatin is a member of the statin drug class and is used to treat hypercholesterolemia, a condition characterized by high levels of cholesterol in the blood. Atorvastatin-d5 is used as a stable isotope-labeled internal standard for bioanalytical research and pharmacokinetic studies.
The chemical formula of Atorvastatin-d5 is C33H32D5FN2O5, and it has a molecular weight of 589.67 g/mol. The deuterium atoms in Atorvastatin-d5 replace the hydrogen atoms in Atorvastatin, making it useful in studies where it is essential to distinguish between the labeled and unlabeled forms of the drug.
Atorvastatin-d5 works by inhibiting the enzyme HMG-CoA reductase, which is responsible for the synthesis of cholesterol in the liver. By reducing cholesterol production, Atorvastatin-d5 can help lower cholesterol levels in the blood, which can reduce the risk of heart disease and stroke.
Like Atorvastatin, Atorvastatin-d5 can cause side effects such as muscle pain, liver damage, and digestive problems. Patients should consult with their doctor before taking Atorvastatin-d5 to ensure that it is safe for them to use. Overall, Atorvastatin-d5 is a useful tool for researchers investigating the pharmacokinetics and metabolism of Atorvastatin and other statin drugs.
