Smiles
O=C(OCC)C1=CC=CC(N=C2OCC)=C1N2CC(C=C3)=CC=C3C4=CC=CC=C4C5=NN=NN5
Therapeutic Uses
Anti-Hypertensives
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
IUPAC Name
Ethyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1Hbenzo[d]imidazole-7-carboxylate
Synonyms
Candesartan Ethyl Ester
Application Notes
Impurity in commercial preparations of Candesartan.
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information
Impurity in commercial preparations of Candesartan.
Refund Policy
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Candesartan Cilexetil EP Impurity A usage and description
Candesartan Cilexetil EP Impurity A, also known as 2-[(2'-carboxy-4-methylbiphenyl-4-yl)methyl]-1H-benzimidazole-7-carboxylic acid, is a chemical impurity that is commonly found in pharmaceutical preparations of Candesartan Cilexetil, a medication used to treat hypertension and heart failure. This impurity is formed during the synthesis of Candesartan Cilexetil and can be present in various amounts in the final product.
The usage of Candesartan Cilexetil EP Impurity A is important to monitor as it may affect the potency and purity of the medication. This impurity can also potentially cause adverse effects on patients, although this has not been extensively studied. Therefore, it is essential to ensure that the level of Candesartan Cilexetil EP Impurity A in pharmaceutical products is within the acceptable limits set by regulatory agencies.
In terms of chemical information, Candesartan Cilexetil EP Impurity A has a molecular formula of C27H21N2O4 and a molecular weight of 447.47 g/mol. It is a white to off-white powder that is sparingly soluble in water and soluble in organic solvents such as methanol and acetonitrile. Its structure contains a benzimidazole ring system and a biphenyl moiety, which are important components for its activity and potential toxicity.
In conclusion, understanding the usage and chemical properties of Candesartan Cilexetil EP Impurity A is crucial for ensuring the quality and safety of medications containing this impurity.