CAS No.
[83799-24-0 (Unlabeled)]
API Family
Carboxyterfenadine
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
Carboxyterfenadine-d3
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Carboxyterfenadine-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Carboxyterfenadine-d3 usage and description
Carboxyterfenadine-D3 is a deuterated form of Carboxyterfenadine, which is an active metabolite of Terfenadine, a second-generation antihistaminic drug. Carboxyterfenadine-D3 is an isotopically labeled compound that is widely used in pharmacological studies to investigate the metabolism and pharmacokinetics of Terfenadine and its metabolites.
Chemically, Carboxyterfenadine-D3 is a carboxylic acid derivative of Terfenadine-D3, with a molecular weight of 362.5 g/mol. It is a white to off-white powder that is soluble in organic solvents such as methanol and acetonitrile.
Carboxyterfenadine-D3 is primarily used as a reference standard in analytical methods such as liquid chromatography-tandem mass spectrometry (LC-MS/MS) to quantify the concentrations of Terfenadine and its metabolites in biological fluids such as plasma, urine, and saliva. It is also used in vitro to study the pharmacodynamics and pharmacokinetics of Terfenadine and its metabolites in different cell cultures and animal models.
In conclusion, Carboxyterfenadine-D3 is a valuable tool for researchers studying the metabolism and pharmacological properties of Terfenadine and its active metabolites. Its isotopic labeling provides a unique advantage in analytical methods to accurately quantify the concentrations of these compounds in biological matrices.
