Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
4-[5-[4-(Methyl-d3)phenyl-2,3,5,6-d4]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
Yes -Refer MSDS for accurate information
Celecoxib-d7 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Celecoxib-d7 usage and description
Celecoxib D7 is a deuterated form of the nonsteroidal anti-inflammatory drug Celecoxib. It is a potent inhibitor of the cyclooxygenase-2 (COX-2) enzyme, which is responsible for the production of prostaglandins that cause inflammation, pain, and fever. It is commonly used for the treatment of various types of arthritis, including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, as well as acute pain and menstrual cramps.
The deuterated form of Celecoxib is used in pharmacokinetic studies to help understand the absorption, distribution, metabolism, and excretion of the drug in the body. Deuterium is a stable isotope of hydrogen that can be used as a tracer to follow the movement of the drug through the body. This helps researchers understand how the drug is processed by the liver and kidneys and how it interacts with other medications.
Celecoxib D7 has a similar chemical structure to Celecoxib, with the addition of seven deuterium atoms. The molecular formula of Celecoxib D7 is C17H9D7N2O2S, with a molecular weight of 329.43 g/mol. The drug is a white to off-white crystalline powder that is insoluble in water but soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO).
In conclusion, Celecoxib D7 is a useful tool for researchers studying the pharmacokinetics of Celecoxib. Its stable isotope properties allow for a better understanding of how the drug is absorbed, distributed, metabolized, and excreted in the body.
