Product Detail
Colchicine-d6
Colchicine Stable Isotopes
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
Colchicine
Storage
Store at refrigerator (2-8°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
Colchicine-d6 Product Information
Colchicine-d6 is listed under Stable Isotopes. It is associated with Colchicine and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-06507.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Colchicine-d6
CAS No.
1217651-73-4
CAT No.
CS-O-06507
Molecular Formula
C₂₂H₁₉D₆NO₆
Molecular Weight
405.47
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
SMILES
O=C(N[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C3=CC=C(OC([2H])([2H])[2H])C(C=C13)=O)C([2H])([2H])[2H]
IUPAC Name
2,2,2-Trideuterio-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(trideuteriomethoxy)-6,7-dihydro-5H-benzo[d]heptalen-7-yl]acetamide
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
"An isotopically labelled antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.;Labeled Colchicine, intended for use as an internal standard for the quantification of Colchicine by GC- or LC-mass spectrometry."
Synonyms
2,2,2-Trideuterio-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(trideuteriomethoxy)-6,7-dihydro-5H-benzo[d]heptalen-7-yl]acetamide
Application Notes
"An isotopically labelled antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.;Labeled Colchicine, intended for use as an internal standard for the quantification of Colchicine by GC- or LC-mass spectrometry."
References
"Lunduena; R,F,; et al,:curr, Opin,cell Biol,; 4; 53 (1992);cccatelli; S,; et al,: Neuroreport; 8; 3779 (1997); Want; T,H,; et al,: J, Biol,chem,; 273; 4928 (1998); Andreu; J,M,; et al,: Bichemistry; 37; 8356 (1998); Jordan; A,; et al,: Med, Res, Rev??c??????????????"
