CAS No.
[1095598-84-7 (Freebase)]
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl-D4]-a-a-diphenyl-3- pyrrolidineacetamide; Hydrochloride
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Darifenacin-d4 Hydrochloride is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Darifenacin-d4 Hydrochloride usage and description
Darifenacin D4 hydrochloride is a medication that is used to treat overactive bladder (OAB) symptoms such as urinary urgency, frequency, and incontinence. It is a selective M3 muscarinic receptor antagonist that works by blocking the neurotransmitter acetylcholine from binding to the M3 receptors in the bladder, leading to a decrease in bladder contractions and an increase in bladder capacity.
Chemically, Darifenacin D4 hydrochloride is a deuterated form of Darifenacin hydrochloride, which means that it contains four deuterium atoms instead of hydrogen atoms. Deuterium is a non-radioactive isotope of hydrogen that can be used in drug development to improve pharmacokinetic properties such as bioavailability and metabolic stability.
The recommended dosage of Darifenacin D4 hydrochloride is 7.5 mg once daily, and it is available in tablet form for oral administration. The medication should be taken with water and swallowed whole, and it should not be crushed or chewed.
Like all medications, Darifenacin D4 hydrochloride may cause side effects such as dry mouth, constipation, blurred vision, and urinary retention. It may also interact with other medications such as ketoconazole, erythromycin, and rifampin.
In conclusion, Darifenacin D4 hydrochloride is a selective M3 muscarinic receptor antagonist used to treat overactive bladder symptoms. It is chemically similar to Darifenacin hydrochloride but contains deuterium atoms, and it should be taken as directed by a healthcare provider.