Therapeutic Uses
Antiretroviral / Anti-HIV
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
Entecavir impurity B, 1367369-77-4
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Entecavir impurity B is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Entecavir impurity B usage and description
Entecavir impurity B is a byproduct that is generated during the synthesis of Entecavir, a widely used antiviral medication that is prescribed for the treatment of hepatitis B virus infections. It is a potent inhibitor of the hepatitis B virus and is commonly used to suppress viral replication, thereby helping to reduce the risk of cirrhosis and liver cancer.
Entecavir impurity B is a key intermediate in the synthesis of Entecavir and is often present in trace amounts in the final product. Although it is not intentionally added to the medication, it is important to monitor its levels during the manufacturing process to ensure that it does not exceed acceptable limits.
Chemically, Entecavir impurity B is a derivative of guanine, which is a purine nucleoside that is found in DNA and RNA. It is classified as a heterocyclic organic compound and has a molecular weight of 303.25 g/mol.
In terms of usage, Entecavir impurity B is primarily used as a reference standard for analytical purposes, particularly in the development and validation of analytical methods for the detection and quantification of Entecavir and its related impurities. It is also used as a starting material for the synthesis of other pharmaceuticals that are based on guanine derivatives.
Overall, Entecavir impurity B plays an important role in the pharmaceutical industry, both as a key intermediate in the synthesis of Entecavir and as a reference standard for analytical purposes. Its chemical properties and analytical characteristics make it an indispensable tool for ensuring the quality and safety of pharmaceutical products that are used to treat hepatitis B virus infections.
