Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
2-[3-[(Hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-5-Thiazolecarboxylic Acid Ethyl Ester
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Febuxostat Impurity 6 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Febuxostat Impurity 6 usage and description
Febuxostat Impurity 6, also known as 2-aminopyrazine-3-carboxylic acid, is a synthetic organic compound that is used as a reference standard and an analytical tool in the quality control and development of febuxostat, a medication used in the treatment of hyperuricemia associated with gout. Febuxostat Impurity 6 is a purine analogue that inhibits the enzyme xanthine oxidase, which plays a crucial role in the production of uric acid in the body. By inhibiting this enzyme, febuxostat and its impurities like Impurity 6, reduce the levels of uric acid in the blood, thereby preventing gout attacks.
Febuxostat Impurity 6 is a white to off-white crystalline powder that is soluble in water and organic solvents. Its chemical formula is C6H6N2O2 and its molecular weight is 138.13 g/mol. It can be synthesized by reacting 2-aminopyrazine with ethyl chloroformate, followed by hydrolysis with sodium hydroxide.
In conclusion, Febuxostat Impurity 6 is an important reference standard that is used in the pharmaceutical industry for the quality control and development of febuxostat. Its chemical properties and inhibitory effects on xanthine oxidase make it an essential analytical tool in the research and development of new drugs for the treatment of gout and hyperuricemia.