Therapeutic Uses
Antiretroviral / Anti-HIV
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
2-Amino-9-[(1,1,2,3,3-pentadeuterio-1,3-dihydroxypropan-2-yl)oxymethyl]-1H-purin-6-one
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
Yes -Refer MSDS for accurate information
Ganciclovir-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
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material handover.
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Ganciclovir-d5 usage and description
Ganciclovir D5 is a modified form of ganciclovir, an antiviral medication used to treat several viral infections, including cytomegalovirus (CMV) infections. The main difference between ganciclovir and Ganciclovir D5 is the presence of five deuterium atoms in the latter, which help to enhance its potency and prolong its half-life in the body.
Ganciclovir D5 works by inhibiting the replication of viral DNA, thus preventing the virus from spreading and causing further damage. It is available in the form of an injectable solution, which is administered intravenously or intravitreally, depending on the condition being treated.
Ganciclovir D5 is primarily used to treat CMV retinitis, a serious eye infection that affects people with weakened immune systems, such as those with HIV/AIDS or undergoing organ transplantation. It is also used for the prevention of CMV disease in transplant recipients who are at high risk of developing the infection.
Chemically, Ganciclovir D5 belongs to the class of guanine analogs and has a molecular formula of C9H9D5N5O3. It has a molecular weight of 277.31 g/mol and a melting point of 250-252ยฐC. It is soluble in water, methanol, and dimethyl sulfoxide.
In conclusion, Ganciclovir D5 is a potent antiviral medication that is widely used to treat CMV infections in immunocompromised patients. Its unique chemical structure and enhanced potency make it a valuable addition to the armamentarium of antiviral drugs.