M.F.
Cโโ
HโโDโNโOโS
Smiles
O=C(NN1CC2CCCC2C1)NS(=O)(C3=C([2H])C([2H])=C(C)C([2H])=C3[2H])=O
Therapeutic Uses
Anti-Diabetic
Storage Condition
Store at freezer (-20ยฐC) for long term storage
IUPAC Name
3-(3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-1-(2,3,5,6-tetradeuterio-4-methylphenyl)sulfonylurea
References
"Duhault; J,; et al,: Arzneimittel-Forch,; 22; 1686 (1972); Holmes; B,; et al,: Drugs; 27; 301 (1984);"
Application Notes
"Labeled Gliclazide, intended for use as an internal standard for the quantification of Gliclazide by GC- or LC-mass spectrometry."
Purity by HPLC
Not less than 95%
Hazard Compound
Refer MSDS for accurate information
"Labeled Gliclazide, intended for use as an internal standard for the quantification of Gliclazide by GC- or LC-mass spectrometry."
Refund Policy
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Gliclazide-d4 usage and description
Gliclazide D4 is a deuterated form of the oral anti-diabetic medication, Gliclazide. It is used in the treatment of type 2 diabetes mellitus, a condition that arises due to the body's inability to produce or effectively use insulin. Gliclazide D4 is specifically designed for use in research studies, including pharmacokinetic and pharmacodynamic studies, where the use of deuterated compounds is necessary for accurate analysis.
The chemical formula for Gliclazide D4 is C15H9D4N3O3S, and it has a molecular weight of 329.43 g/mol. The deuterated form of Gliclazide is created by replacing four hydrogen atoms with deuterium atoms, which are isotopes of hydrogen with a slightly higher mass. This modification does not change the therapeutic effects or mechanism of action of the medication, but it does allow for more precise determination of drug concentrations in biological samples.
Gliclazide D4 works by stimulating the pancreas to release insulin, which helps to lower blood sugar levels. It does this by binding to specific receptors on the beta cells of the pancreas, which triggers the release of insulin. Gliclazide D4 is typically administered orally, and its effects can last for up to 24 hours.
In conclusion, Gliclazide D4 is a deuterated form of the oral anti-diabetic medication, Gliclazide, which is used in research studies for accurate analysis. Its chemical formula is C15H9D4N3O3S, and it works by stimulating the pancreas to release insulin. Gliclazide D4 is a valuable tool for researchers studying the pharmacokinetics and pharmacodynamics of anti-diabetic medications.