Therapeutic Uses
Anti-Fungals
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl-d9)-3H-1,2,4-triazol-3-one
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
No -Refer MSDS for accurate information
Itraconazole-d9 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Itraconazole-d9 usage and description
Itraconazole D9 is a deuterated form of Itraconazole, which is an antifungal medication that belongs to the azole class of drugs. It is commonly used to treat a variety of fungal infections such as aspergillosis, blastomycosis, histoplasmosis, and candidiasis. It works by inhibiting the synthesis of ergosterol, which is a crucial component of fungal cell membranes, thereby disrupting their growth and replication.
Itraconazole D9 is an isotopically labeled compound that is useful in pharmacokinetic and bioavailability studies. The deuterium substitution at the 9th position of the Itraconazole molecule provides a unique tool for tracing the metabolic fate of the drug in vivo. It is often used in pharmacological research to determine the metabolic pathways and drug-drug interactions of Itraconazole.
The chemical formula of Itraconazole D9 is C35H38D9N5O4, and its molecular weight is 622.87 g/mol. The compound is a white to off-white powder that is sparingly soluble in water but soluble in organic solvents like methanol and ethanol.
In summary, Itraconazole D9 is a specialized form of Itraconazole that is used in pharmacokinetic and bioavailability studies. Its deuterium substitution provides a unique tool for tracing the metabolic fate of the drug, making it an essential compound in pharmacological research.
