Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
3,5-Diethyl 4-[2-[(1E)-3-(1,1-dimethylethoxy)-3-oxo-1-propen-1-yl]phenyl]-1,4-dihydro-2,6-di(methyl-13C)-3,5-pyridine-2,3,5,6-13C4-dicarboxylate-3,5-13C2
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Lacidipine-13C8 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Lacidipine-13C8 usage and description
Lacidipine 13C8 is a labeled version of the calcium channel blocker lacidipine, which is used to treat hypertension or high blood pressure. This medication works by blocking the entry of calcium into the smooth muscles lining the blood vessels, which relaxes them and leads to a reduction in blood pressure. Lacidipine 13C8 contains eight carbon-13 isotopes, which can be used in pharmacokinetic studies to track the metabolism and distribution of the drug in the body.
The molecular formula of Lacidipine 13C8 is C32H34N3O6Cl, and its molecular weight is 594.1 g/mol. It is a white to yellowish crystalline powder that is soluble in organic solvents like methanol and ethanol. The drug is typically administered orally as tablets or capsules, with the recommended dose ranging from 2 to 4 mg per day.
Lacidipine 13C8 is metabolized in the liver and excreted in the urine and feces. Its elimination half-life is around 13 hours, and its plasma protein binding is approximately 98%. The drug is primarily eliminated through hepatic metabolism, with the major metabolite being M1, which is formed by hydrolysis of the ester group. Lacidipine 13C8 may interact with other medications or substances, so patients should consult their healthcare provider before taking it. Overall, Lacidipine 13C8 is a useful tool for studying the pharmacokinetics and metabolism of lacidipine, which can help improve its clinical efficacy and safety.
