Synonyms
Levothyroxine Sodium EP Impurity J;L-3,3- Diiodothyronine;L-3,3- Diiodothyronine; (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid;Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]-, L- (8CI);(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Levothyroxine Sodium EP Impurity J is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Levothyroxine Sodium EP Impurity J usage and description
Levothyroxine Sodium EP Impurity J is a chemical compound that is used in the pharmaceutical industry as a reference standard for the quality control of levothyroxine sodium, which is a synthetic form of thyroid hormone. The compound is also known as 3,3',5-triiodothyroacetic acid or T3AC, and it is a metabolite of levothyroxine that is formed in the body during the metabolism of the drug.
Levothyroxine is used to treat hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormone. The drug is also used to treat certain types of thyroid cancer and goiter. The presence of Levothyroxine Sodium EP Impurity J in the drug can affect the efficacy and safety of the medication, which is why it is important to monitor its levels during manufacturing and storage.
The chemical information of Levothyroxine Sodium EP Impurity J includes its molecular formula, which is C15H12I3NO4, and its molecular weight, which is 672.97 g/mol. The compound is a white to off-white powder that is soluble in water, ethanol, and methanol. It has a melting point of 153-155ยฐC and a purity of at least 98%.
In conclusion, Levothyroxine Sodium EP Impurity J is an important reference standard in the pharmaceutical industry that is used to ensure the quality of levothyroxine sodium. Its chemical properties and usage are crucial for the safe and effective treatment of hypothyroidism and other thyroid-related conditions.