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Linaclotide



Linaclotide Cas No.851199-59-2

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  • Synonyms:DL-cysteinyl-DL-cysteinyl-DL-alpha-glutamyl-DL-tyrosyl-DL-cysteinyl-DL-cysteinyl-DL-asparagyl-DL-prolyl-DL-alanyl-DL-cysteinyl-DL-threonyl-glycyl-DL-cysteinyl-DL-tyrosine (1->6),(2->10),(5->13)-tris(disulfide)
  • Chemical Name:(2S)-2-[[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(2-amino-2-oxoethyl)-27-(2-carboxyethyl)-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo-18,19,35,36,48,49-hexathia-2,5,11,14,23,26,29,32,39,42,45,52-dodecazatetracyclo[22.22.4.216,33.07,11]dopentacontane-38-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
  • Country of Origin:India
  • Application Notes:NULL
  • Product Category:Linaclotide API Standards

    Linaclotide is identified by CAS No. 851199-59-2 and is chemically known as DL-cysteinyl-DL-cysteinyl-DL-alpha-glutamyl-DL-tyrosyl-DL-cysteinyl-DL-cysteinyl-DL-asparagyl-DL-prolyl-DL-alanyl-DL-cysteinyl-DL-threonyl-glycyl-DL-cysteinyl-DL-tyrosine (1->6),(2->10),(5->13)-tris(disulfide), IUPAC Name: (2S)-2-[[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(2-amino-2-oxoethyl)-27-(2-carboxyethyl)-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo-18,19,35,36,48,49-hexathia-2,5,11,14,23,26,29,32,39,42,45,52-dodecazatetracyclo[22.22.4.216,33.07,11]dopentacontane-38-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid.

    Linaclotide is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Linaclotide.


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