Therapeutic Uses
Immunosuppressants
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Methotrexate EP Impurity I, 66147-29-3
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 95%
Hazard Compound
No -Refer MSDS for accurate information
Methotrexate EP Impurity I is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Methotrexate EP Impurity I usage and description
Methotrexate EP Impurity I is a chemical compound that is used in pharmaceutical research and development. This impurity is a known byproduct of the synthesis of Methotrexate, a chemotherapy drug used to treat a variety of cancers and autoimmune disorders. Methotrexate EP Impurity I is typically used as a reference standard in the analysis and identification of Methotrexate and its related compounds.
Chemically, Methotrexate EP Impurity I is a dihydroxymethotrexate derivative, which means that it is structurally similar to Methotrexate but contains additional hydroxyl groups. This impurity is considered to be a potential impurity in Methotrexate drug substance and drug product due to its structural similarity with Methotrexate. Therefore, it is important to monitor and control its levels during the manufacturing process.
The usage of Methotrexate EP Impurity I is critical in the quality control of Methotrexate products. It is used in the development and validation of analytical methods such as high performance liquid chromatography (HPLC) and mass spectrometry (MS) to ensure the purity and potency of Methotrexate drug products. The accurate identification and quantification of Methotrexate EP Impurity I is essential to ensure the safety and efficacy of Methotrexate therapy.