Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((piperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)benzamide
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
N-Desmethyl Imatinib-d8 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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N-Desmethyl Imatinib-d8 usage and description
N-Desmethyl Imatinib D8 is a deuterated form of N-desmethyl imatinib, which is a metabolite of imatinib. Imatinib is a drug used in the treatment of chronic myeloid leukemia (CML). It works by inhibiting the activity of certain enzymes that are responsible for the growth of cancer cells. N-desmethyl imatinib is a major metabolite of imatinib and is believed to have similar pharmacological properties.
N-Desmethyl Imatinib D8 is used as a reference standard in pharmaceutical research and development. It is also used in pharmacokinetic studies to determine the metabolism and elimination of imatinib and its metabolites. The deuterium atoms present in N-Desmethyl Imatinib D8 can be used as a tracer to study the pharmacokinetics of imatinib in vivo.
The chemical formula of N-Desmethyl Imatinib D8 is C26H20D8N7O, and its molecular weight is 455.53 g/mol. It is a white to off-white powder that is soluble in dimethyl sulfoxide and methanol. The compound is stable under normal storage conditions and does not require any special handling procedures.
In conclusion, N-Desmethyl Imatinib D8 is a deuterated form of N-desmethyl imatinib that is used as a reference standard in pharmaceutical research and development. It is also used in pharmacokinetic studies to determine the metabolism and elimination of imatinib and its metabolites.
