Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
6-Methylaminopurine ribonucleoside; 6-Methylaminopurine riboside; 9-β-D-Ribofuranosyl-N6-methylaminopurine; N6-Methyladenosine; N6-methyladenosine (m6A)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
N6-Methyladenosine is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
N6-Methyladenosine usage and description
N6-Methyladenosine (m6A) is a modified nucleotide that is present in RNA molecules. It is formed by the addition of a methyl group to the sixth position of the adenine base. This modification is the most prevalent internal modification in eukaryotic messenger RNA (mRNA), and is also found in other types of RNA such as transfer RNA (tRNA) and ribosomal RNA (rRNA).
The function of m6A in mRNA is not fully understood, but it is believed to play a role in regulating mRNA stability, processing, and translation. The modification can be added or removed dynamically, and is regulated by a set of enzymes called “writers”, “erasers”, and “readers”. The writers are responsible for adding the methyl group, while the erasers remove it. The readers recognize and bind to the m6A modification, and can influence various aspects of mRNA metabolism.
In addition to its role in RNA regulation, m6A has also been implicated in various diseases, including cancer and neurological disorders. Aberrant m6A levels have been observed in different types of cancer, and targeting the m6A pathway has emerged as a potential therapeutic strategy.
From a chemical perspective, m6A is a relatively small modification, but it can have a significant impact on RNA structure and function. Its presence can affect base pairing, stacking interactions, and hydrogen bonding, which can in turn influence RNA folding and recognition by proteins. The study of m6A and its effects on RNA biology continues to be an active area of research.
