Storage Condition
Store at refrigerator (2-8°C) for long term storage
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Nicardipine-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Nicardipine-d3 usage and description
Nicardipine-D3 is a deuterated version of the calcium channel blocker Nicardipine. It is commonly used in the treatment of high blood pressure, angina, and other cardiovascular conditions. Nicardipine-D3 is a selective dihydropyridine calcium channel blocker that works by inhibiting the influx of calcium ions into vascular smooth muscle cells and cardiac myocytes.
The deuterium substitution in Nicardipine-D3 provides a useful tool for pharmacokinetic and pharmacodynamic studies. Deuterium is a stable isotope of hydrogen that has a slightly higher mass, which can result in slower metabolism and elimination of the drug from the body. This can lead to longer-lasting and more consistent drug effects, making Nicardipine-D3 a valuable tool in clinical research.
In terms of chemical information, Nicardipine-D3 has a molecular formula of C26H27D3N2O6 and a molecular weight of 471.57 g/mol. It has a half-life of approximately 8 hours and is primarily metabolized in the liver. Nicardipine-D3 is available in both oral and intravenous formulations and is typically administered under medical supervision.
Overall, Nicardipine-D3 is a valuable drug for the treatment of cardiovascular conditions and for use in clinical research. Its deuterium substitution provides a useful tool for pharmacokinetic and pharmacodynamic studies, and its selective calcium channel blocking properties make it a highly effective treatment option.
