Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Nilotinib-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Nilotinib-d3 usage and description
Nilotinib D3 is a deuterated form of the drug Nilotinib, which is a tyrosine kinase inhibitor used in the treatment of chronic myelogenous leukemia (CML). It works by inhibiting the activity of an abnormal protein called BCR-ABL, which is responsible for the growth and survival of cancer cells in CML patients. Nilotinib D3 is used in research and clinical studies to determine the pharmacokinetic properties of Nilotinib and to help identify any potential drug-drug interactions that may occur.
Chemically, Nilotinib D3 is a white to off-white powder with a molecular formula of C28H23D3ClN6O and a molecular weight of 503.02 g/mol. It is soluble in methanol and slightly soluble in water. The deuterium substitution in Nilotinib D3 helps to improve the drug’s metabolic stability and bioavailability, resulting in a longer half-life and more efficient delivery to cancer cells.
Nilotinib D3 is typically administered orally in the form of capsules, and the recommended dosage varies depending on the patient’s weight and medical history. Common side effects of Nilotinib D3 include nausea, vomiting, diarrhea, and skin rash. Patients should also be monitored for any signs of liver toxicity and heart problems, as Nilotinib can cause these complications in some cases.
Overall, Nilotinib D3 is a valuable tool for researchers and clinicians working to improve the treatment of CML and other types of cancer. Its unique chemical properties and therapeutic benefits make it an important addition to the arsenal of drugs used in the fight against cancer.
