Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
7-epi-Paclitaxel; 7-Epitaxol;7-epi-Taxol
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Paclitaxel EP Impurity E is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
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Paclitaxel EP Impurity E usage and description
7-Epipaclitaxel is a semi-synthetic derivative of paclitaxel, which is a natural product extracted from the bark of the Pacific yew tree. It is a chemotherapy drug used in the treatment of various types of cancer, including breast cancer, lung cancer, and ovarian cancer. 7-Epipaclitaxel works by preventing the division of cancer cells, thus inhibiting their growth and spreading throughout the body.
The chemical formula of 7-Epipaclitaxel is C47H51NO14, and its molecular weight is 853.91 g/mol. It is a white to pale yellow crystalline powder that is soluble in methanol, ethanol, and dimethyl sulfoxide. The drug is administered through intravenous injection, and the dosage and duration of treatment depend on the type and stage of cancer being treated.
Like paclitaxel, 7-Epipaclitaxel binds to microtubules within cancer cells, stabilizing them and preventing them from breaking down during cell division. This leads to the accumulation of cells in the G2/M phase of the cell cycle, ultimately leading to cell death. However, 7-Epipaclitaxel has been shown to have similar or better antitumor activity than paclitaxel, with fewer side effects, making it a promising alternative for cancer treatment.
In conclusion, 7-Epipaclitaxel is an effective chemotherapy drug used in the treatment of various types of cancer. Its chemical structure and mechanism of action are similar to those of paclitaxel, but it has been shown to have fewer side effects. As such, it is a promising alternative for cancer treatment that warrants further research and development.
