Storage Condition
Keep in a tightly closed vial, store in refrigerator
IUPAC Name
3-(2-(4-benzhydrylpiperazin-1-yl)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
References
"Meguro, K,, et al,: Chem, Pharm, Bull,, 33, 3787 (1985), Mizuno, K,, et al,: Curr, Ther, Res,, 52, 248 (1992)"
Application Notes
Labelled (R)-Manidipine enantiomer.
Hazard Compound
Refer MSDS for complete information
R-(-)-Manidipine-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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R-(-)-Manidipine-d4 usage and description
R-(-)-Manidipine D4 is a chiral compound which is used for research purposes in drug development and pharmacological studies. It is a calcium channel blocker that is used to treat high blood pressure and angina. It is an isotope-labeled compound that is used in studies to determine the pharmacokinetics and metabolic pathways of the drug.
The chemical formula of R-(-)-Manidipine D4 is C35H37D4N3O6 and its molecular weight is 617.76 g/mol. Its chemical structure consists of a dihydropyridine ring that contains a nitrogen atom and three deuterium atoms. It is a white crystalline powder that is soluble in water and ethanol.
R-(-)-Manidipine D4 works by blocking the calcium channels in the smooth muscle cells of the blood vessels, which reduces the amount of calcium that enters the cells. This causes the blood vessels to relax, which decreases the resistance in the vessels and lowers blood pressure. It also improves the blood flow to the heart, which relieves angina.
In conclusion, R-(-)-Manidipine D4 is a useful compound in pharmacological studies and drug development for hypertension and angina. Its chemical properties and mechanism of action make it an important tool in understanding the pharmacokinetics and metabolic pathways of this class of drugs.
