Therapeutic Uses
Anti-Hypertensives
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
(4R)-2-[[2-Amino(ethoxy-d4)]methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
R-Amlodipine-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
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basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
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R-Amlodipine-d4 usage and description
R-Amlodipine D4 is a deuterated form of the calcium channel blocker R-amlodipine. It is used to treat hypertension and angina, by relaxing blood vessels and improving blood flow. R-amlodipine D4 is a dihydropyridine calcium channel blocker that selectively inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle. This results in vasodilation of the peripheral arterioles and reduces the workload on the heart, which can help to lower blood pressure and reduce the frequency and severity of angina attacks.
The deuterium substitution in R-Amlodipine D4 provides several benefits. Firstly, it increases the half-life of the drug, meaning that it can remain in the body for longer periods of time, providing a sustained effect. Additionally, deuterated drugs have been shown to have increased metabolic stability, which can reduce the risk of toxicity and side effects.
R-amlodipine D4 is typically administered orally, with the dosage prescribed by a healthcare professional depending on the individual patient's needs and medical history. It is important to follow the prescribed dosage and not exceed the recommended amount, as this can increase the risk of side effects such as dizziness, headaches, and swelling of the ankles.
Overall, R-Amlodipine D4 is a widely used calcium channel blocker that can help to manage hypertension and angina. Its deuterium substitution provides increased stability and a longer half-life, allowing for a sustained therapeutic effect.
