Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
Ruxolitinib, SEM Pyrimidine Impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Ruxolitinib, SEM Pyrimidine Impurity usage and description
4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine is a chemical compound that belongs to the family of pyrrolopyrimidine derivatives. This compound has a molecular formula of C17H25N5OSi and a molecular weight of 359.48 g/mol.
This compound is commonly used in biomedical research as a potential inhibitor of certain enzymes involved in cancer cell growth and proliferation. It has been shown to selectively inhibit the activity of a protein kinase called CDK7, which plays an important role in the regulation of cell cycle progression and transcriptional control. CDK7 inhibition has been suggested as a potential therapeutic strategy for various types of cancer.
The chemical structure of 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine contains a pyrrolopyrimidine core, which is fused to a pyrazole ring and a trimethylsilyl group. The trimethylsilyl group is important for the stability and solubility of the compound, as well as for its pharmacological activity.
Overall, 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine is a promising compound for cancer research and drug development, owing to its potent and selective inhibition of CDK7 activity. Further studies are needed to fully understand its mechanism of action and potential therapeutic applications.
