Therapeutic Uses
Anti-Fungals
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(αR,βS)-6-Chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol (ACI); 4-Pyrimidineethanol, 6-chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, [R-(R*,S*)]- (ZCI)
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
Yes -Refer MSDS for accurate information
Voriconazole (RR,beta)-6-Chloro Impurity-rac-6-Chloro Voriconazole is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Voriconazole (RR,beta)-6-Chloro Impurity-rac-6-Chloro Voriconazole usage and description
Voriconazole is a triazole antifungal medication used to treat a variety of fungal infections, including aspergillosis, candidiasis, and cryptococcosis. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes, thus preventing fungal growth and replication.
(RR,β)-6-Chloro Impurity-rac-6-Chloro Voriconazole is a chemical intermediate used in the synthesis of voriconazole. It is a chiral impurity that can exist in two enantiomeric forms, RR and SS. The RR form is the desired product, as it is the active ingredient in voriconazole, while the SS form is inactive.
Chemically, (RR,β)-6-Chloro Impurity-rac-6-Chloro Voriconazole is a racemic mixture of the two enantiomers. It has a molecular weight of 349.27 g/mol and a molecular formula of C16H14Cl2N4O.
In terms of usage, (RR,β)-6-Chloro Impurity-rac-6-Chloro Voriconazole is primarily used in the pharmaceutical industry as an intermediate in the synthesis of voriconazole. It is important to ensure that the final product contains only the RR enantiomer, as the SS enantiomer is inactive and may cause adverse side effects if present in significant amounts.
Overall, (RR,β)-6-Chloro Impurity-rac-6-Chloro Voriconazole plays a crucial role in the production of voriconazole and in the treatment of fungal infections. Its chemical properties and usage highlight the importance of chiral purity in pharmaceutical synthesis and the impact it can have on the efficacy and safety of drugs.
